Sakari Mäntyselkä

Sakari Mäntyselkä

Doctoral Researcher
Unit
Faculty of Sport and Health Sciences
Room number
Email
sakari.a.mantyselka@jyu.fi
Postal address
Rautpohjankatu 8

Biography

I am a Doctoral Researcher in exercise physiology. My background is in cell and molecular biology (M.Sc.). I use various (bio)chemical research methods including liquid chromatography-mass spectrometry, NMR spectroscopy, immunoblotting, and cell culture.

Research interests

I study the role of specific cellular metabolic pathways in muscle size regulation. I also investigate how strength training or mechanical loading of cultured muscle cells affects these metabolic pathways and which metabolites are secreted by the muscle cells into the extracellular space.

Publications

Publication
2024

American Journal of Physiology : Endocrinology and Metabolism
Mäntyselkä, Sakari
Kolari, Kalle
Baumert, Philipp
Ylä-Outinen, Laura
Kuikka, Lauri
Lahtonen, Suvi
Permi, Perttu
Wackerhage, Henning
Kalenius, Elina
Kivelä, Riikka
Hulmi, Juha J.
Publication
2024

Journal of Cachexia, Sarcopenia and Muscle
Baumert, Philipp
Mäntyselkä, Sakari
Schönfelder, Martin
Heiber, Marie
Jacobs, Mika Jos
Swaminathan, Anandini
Minderis, Petras
Dirmontas, Mantas
Kleigrewe, Karin
Meng, Chen
Gigl, Michael
Ahmetov, Ildus I.
Venckunas, Tomas
Degens, Hans
Ratkevicius, Aivaras
Hulmi, Juha J.
Wackerhage, Henning
Publication
2022

Metabolites
Karvinen, Sira
Fachada, Vasco
Sahinaho, Ulla-Maria
Pekkala, Satu
Lautaoja, Juulia H.
Mäntyselkä, Sakari
Permi, Perttu
Hulmi, Juha J.
Silvennoinen, Mika
Kainulainen, Heikki
Publication
2021

American Journal of Physiology : Endocrinology and Metabolism
Lautaoja, Juulia H.
O'Connell, Thomas
Mäntyselkä, Sakari
Peräkylä, Juuli
Kainulainen, Heikki
Pekkala, Satu
Permi, Perttu
Hulmi, Juha J.

Research groups

Hulmi lab
Research group

Hulmi Lab - Muscle and Exercise Metabolism (MEM)

We study metabolism at the whole body, muscle and cellular levels using a variety of in vivo and in vitro research models. We make use of the latest research methods in physiology and life sciences, such as multi-omics and labelling experiments.

Projects

Metabolic rewiring of muscle glucose metabolism
Project

MeRWi (Metabolic ReWiring of muscle cell glucose metabolism)

We investigate whether muscle cells behave in a cancer cell-like manner, producing vital compounds in the glycolytic pathways and what role this phenomenon plays in muscle size regulation and secretion of small molecule metabolites.
tradere_picture
Project

TraDeRe (Resistance TRAining, DEtraining, and REtraining)

The TraDeRe2 project investigates intra- and inter-individual variation in resistance training responses. The aim is to identify the determinants of individual variation in resistance training, detraining and retraining.