Exercise, Extracellular Vesicles and Senescence (EEVaS) - Molecular mechanisms promoting healthspan

Age is the main risk factor for the prevalent chronic diseases of developed countries. This fact has raised the question whether we should treat aging instead of treating individual diseases. Accumulation of senescent cells with age underlie several chronic diseases, whereas exercise diminishes the markers of cellular senescence. The biological significance of cellular senescence on healthy aging remains yet to be fully understood.

Exercise, Extracellular Vesicles and Senescence (EEVaS) study aims to establish the key signaling molecules mediating the senolytic effects of exercise. The study will be carried out at the Gerontology Research Center, Faculty of Sport and Health Sciences, Ä¢¹½Ö±²¥, Finland. When successful, the results of EEVaS study have potential to be translational to human health in delaying the onset of age-related chronic diseases and hence, increasing healthspan.
Kuvituskuva viestirakkuloista

Table of contents

Project duration
-
Core fields of research
Physical activity, health and wellbeing
Research areas
Molecular mechanisms of exercise and health
Faculty
Faculty of Sport and Health Sciences
Funding
Research Council of Finland